Evaluation of some important physicochemical properties of starch free grewia gum
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منابع مشابه
Starch-free grewia gum matrices: Compaction, swelling, erosion and drug release behaviour.
Polysaccharides are suitable for application as hydrophilic matrices because of their ability to hydrate and swell upon contact with fluids, forming a gel layer which controls drug release. When extracted from plants, polysaccharides often contain significant quantities of starch that impacts upon their functional properties. This study aimed to evaluate differences in swelling, erosion and dru...
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Purpose: To study the mechanical and dynamic swelling properties of grewia gum, evaluate its compression behaviour and determine the effect of drying methods on its properties. Methods: Compacts (500 mg) of both freeze-dried and air-dried grewia gum were separately prepared by compression on a potassium bromide (KBr) press at different pressures and subjected to Heckel analysis. Swelling studie...
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Matrix-based tablets using 40 %w/w grewia gum were prepared by direct compression to contain cimetidine as novel drug. The formulations were compared with similar formulations using hydroxypropyl methylcelluose (Methocel), gum arabic, carboxy methylcellulose (Blanose), or ethyl cellulose (Ethocel) as polymer matrix. Also binary composite matrices containing grewia gum and the reference polymers...
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